内容摘要：For her two full-term pregnancies, she could have prenatal visits with a doctor, a midwife or both. She had additional regular appointments with a high-risk OB-GYN because of a chronic health condition, and said she “felt very well cared for.”

For her two full-term pregnancies, she could have prenatal visits with a doctor, a midwife or both. She had additional regular appointments with a high-risk OB-GYN because of a chronic health condition, and said she “felt very well cared for.”

The FDA’s credibility has long rested on the independence of its scientific decisions. While the agency is led by a handful of political appointees, approval decisions are almost always handled by career scientists.But that standard appears to be shifting. FDA staffers were poised to approve

early last month but the decision was delayed by administration officials, including Makary, according to two people with direct knowledge of the situation who spoke on condition of anonymity to discuss agency matters. The shot was approved late Friday with unusual restrictions.Dr. Tracy Beth Hoeg — a political appointee serving as Makary’s special assistant — was involved in the unprecedented demand that Novavax conduct a new clinical trial of its shot after approval, according to the people. The requirement came shortly after the agency’s longtime vaccine chief,, was forced to resign.

Hoeg — along with Makary and Prasad — spent much of the COVID-19 pandemic criticizing the FDA’s handling of booster shots, particularly in children and young adults. All three were co-authors of a 2022 paper stating that requiring booster shots in young people would cause more harm than benefit.Novavax isn’t the only vaccine manufacturer already affected by changing attitudes at FDA. Earlier this month, Moderna pushed back the target date for its new COVID-and-flu combination vaccine to next year after the FDA requested additional effectiveness data.

As the FDA’s top official overseeing vaccines, Prasad is now in position to reverse what he recently called “a number of missteps” in how the FDA assessed the benefits and risks of COVID-19 boosters.

He questioned how much benefit yearly vaccinations continue to offer. In a podcast shortly before assuming his FDA job, Prasad suggested companies could study about 20,000 older adults in August or September to show if an updated vaccine prevented COVID-related hospitalizations.Alito described the book as an endorsement of same-sex marriage. “The book has a clear message, and a lot of people think it’s a good message, and maybe it is a good message, but it’s a message that a lot of people who hold on to traditional religious beliefs don’t agree with,” he said.

In all, five books are at issue in the high court case, touching on the same themes found in classic stories that include Snow White, Cinderella and Peter Pan, the school system’s lawyers wrote.In “Prince and Knight,” two men fall in love after they rescue the kingdom, and each other. “Love, Violet” deals with a girl’s anxiety about giving a valentine to another girl. “Born Ready” is the story of a transgender boy’s decision to share his gender identity with his family and the world. “Intersection Allies” describes nine characters of varying backgrounds, including one who is gender-fluid.

Billy Moges, a board member of the Kids First parents’ group that sued over the books, said the content is sexual, confusing and inappropriate for young schoolchildren.The writers’ group Pen America said in a court filing what the parents want is “a constitutionally suspect book ban by another name.” Pen America reported more than 10,000 books were banned in the last school year.