It’s unknown how many in the Mennonite community have gotten the vaccine — which is safe, with risks lower than those of measles complications.
Hsu, now 26, is the first to return as an adult and test if reimplanting those cells might work.“The science behind it is so incredibly new that right now it’s kind of a waiting game,” said Hsu, of Vienna, Virginia. “It’s kind of eagerly crossing our fingers and hoping for the best.”
It may seem unusual to discuss future fertility when a family is reeling from the diagnosis of a child’s cancer. But 85% of children with cancer now survive to adulthood and about 1 in 3 are left infertile from chemotherapy or radiation.Young adults with cancer can bank sperm, eggs or sometimes embryos ahead of treatment. But children diagnosed before puberty don’t have that option because they’re not yet producing mature sperm or eggs.Boys are born with stem cells inside spaghetti-like tubes in the testes, cells that start producing sperm after puberty sparks a rise in testosterone. With
, Pitt reproductive scientist Kyle Orwig studies how to preserve and potentially use testicular cells to restore fertility.This article is part of AP’s Be Well coverage, focusing on wellness, fitness, diet and mental health.
It starts with a biopsy-like removal of a small amount of testicular tissue that contains millions of cells – some of them precious sperm-producing stem cells.
from about 1,000 prepubertal boys.Lots of extra steps come before and after surgery.
First, what pig to use: Some have up to 10 genetic changes but Montgomery is betting one is enough — removal of a single porcine gene that triggers an immediate immune attack.While the pigs are housed in a germ-free facility, researchers performed extra testing for any hidden infection. Everyone in the operating room must have certain vaccinations and undergo blood tests of their own.
Surgery over, doctors wheeled Miller’s body into the same ICU room where five years earlier Montgomery had recovered from his heart transplant.Next came more intense testing than living patients could tolerate. Every week doctors biopsy the kidney, putting samples under the microscope to spot any hints of rejection. Blood is continually monitored, the spleen got a peek, and nurses keep close watch that the body is being properly maintained on the ventilator.