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“These are precious animals,” said David Ayares of Revivicor Inc., who spent decades learning to clone pigs with just the right genetic changes to allowThe biosecurity gets even tighter just a few miles away in Christiansburg, Virginia, where a new herd is being raised – pigs expected to supply organs for formal studies of animal-to-human transplantation as soon as next year.

This massive first-of-its-kind building bears no resemblance to a farm. It’s more like a pharmaceutical plant. And part of it is closed to all but certain carefully chosen employees who take a timed shower, don company-provided clothes and shoes, and then enter an enclave where piglets are growing up.Behind that protective barrier are some of the world’s cleanest pigs. They breathe air and drink water that’s better filtered against contaminants than what’s required for people. Even their feed gets disinfected – all to prevent them from picking up any possible infections that might ultimately harm a transplant recipient.“We designed this facility to protect the pigs against contamination from the environment and from people,” said Matthew VonEsch of United Therapeutics, Revivicor’s parent company. “Every person that enters this building is a possible pathogen risk.”

The Associated Press got a peek at what it takes to clone and raise designer pigs for their organs – including a $75 million “designated pathogen-free facility” built to meet Food and Drug Administration safety standards for xenotransplantation.Thousands of Americans each year

for a transplant, and many experts acknowledge there never will be enough human donors to meet the need.

Animals offer the tantalizing promise of a ready-made supply. After decades of failed attempts, companies including Revivicor,“It’s a miracle,” Dancyg told The Associated Press on Wednesday, hours after being reunited with her now 3 1/2-year old Cavalier King Charles spaniel. “It doesn’t make sense ... People didn’t survive. How did she?”

The reunion brought a rare touch of joy in Israel after 18 months of devastating war.The Oct. 7, 2023, Hamas attack killed some 1,200 people and resulted in more than 250 others being kidnapped. Nearly 60 hostages remain in Gaza, more than half of whom are believed to be dead.

An Israeli offensive launched after the attack has killed more than 51,000 Palestinians, more than half of them women and children, according to local health authorities, and reduced large parts of Gaza to rubble. U.S.-led efforts to broker a ceasefire and bring home remaining hostages appear to be at a standstill.Nir Oz was one of the